233 Colanic acid (capsular isopolysaccharide acid), a common gut bacterial metabolite extracted from five bacterial mutants, has been confirmed to extend the lifespan of nematodes and Drosophila by regulating ER stress and mitochondrial dynamics in host cells
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Gabrielle Lyon is an accomplished physician and the New York Times bestselling author of FOREVER STRONG: A New, Science-Based Strategy for Aging Well and author of upcoming book, The Forever Strong PLAYBOOK, releasing on January 27, 2026
In this context, it has been demonstrated that the restoration of -cell mass can occur not only through proliferation of existing -cells but also via transdifferentiation of other pancreatic cell types, such as -, -, PP-, and ductal epithelial cells (Figure 1B)
These reference intervals will serve as a crucial guide for health screening and support the diagnosis and treatment of clinically relevant diseases.